fa تخصصي Special پژوهشي Research <span style="font-size:11pt"><span style="line-height:120%"><span style="font-family:Calibri,sans-serif"><span style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times="">The study is on the toxic effects of Bisphenol A in <i>Cyprinus carpio</i>, an Indian freshwater fish, presumably highly nutritious in proteins, and one that finds extensive usage in aquaculture establishments. BPA ranks very high among dispersing contaminants in freshwater systems, chiefly wetlands; hence, pressing attention is warranted. Thereafter, a certain set of hematological, histological, and biochemical parameters had been observed on the seventh day following exposure to BPA at sub-lethal concentrations of 0.1, 0.2, and 0.5 mg/L. The amount of RBC showed a decreasing trend from 2.95&times;10⁶ to 2.3&times;10⁶ Cells/mm³ in 0.5 mg/L dose. However, the hemoglobin concentration, an opposite trend was observed, from 11.2 g/dL in control to 8.5 g/dL concentration. An opposite trend was noticed in WBC counts that increased from 9.1&times;10³ to 13.4&times;10³ Cells/mm3 at 0.5 mg/L, thus indicating hematological stress and activation of immune defense. Degeneration in testes and ovaries of fish, implicated through observed histological changes, further corroborates the estrogenic effect of BPA. This was accompanied by a reduction in antioxidant enzyme activities and an elevation in lipid peroxidation, a classical indicator of oxidative stress. Given such findings, the present study emphatically argues against BPA to reduce its effect on aquatic life, thereby affecting the environment and food safety. </span></span></span></span></span></span><br> &nbsp; Bisphenol A (BPA), Cyprinus Carpio, Hematological, Histological, Oxidative Stress 55 66 http://injbir.com/browse.php?a_code=A-10-1-26&slc_lang=fa&sid=1 A. Iswaran Yes Assistant Professor, Department of Zoology, Kongunadu Arts and Science College, Coimbatore-641029, India M. Poorani No Assistant Professor, Department of Zoology, Kongunadu Arts and Science College, Coimbatore-641029, India S. Raja No Assistant Professor, Department of Zoology, Kongunadu Arts and Science College, Coimbatore-641029, India